Uluisik I~Koc A, 2011

Pubmed ID 21035538
Title Genome-wide identification of genes that play a role in boron stress response in yeast.
Authors Irem Uluisik, Alaattin Kaya, Ercan S Unlu, Kadir Avsar, Huseyin C Karakaya, Talat Yalcin, Ahmet Koc
Abstract Boron is an essential micronutrient for plants and it is either necessary or beneficial for animals. Studies identified only few genes related to boron metabolism thus far and details of how boron is imported into cells and used in cell metabolism are largely unknown. In order to identify genes that play roles in boron metabolism, we screened the entire set of yeast haploid deletion mutants and identified 6 mutants that were resistant to toxic levels of boron, and 21 mutants that were highly sensitive to boron treatment. Furthermore, we performed a proteomic approach to identify additional proteins that are significantly up-regulated by boron treatment. Our results revealed many genes and pathways related to boron stress response and suggest a possible link between boron toxicity and translational control.
Citation Genomics 2011; 97:106-11

Datasets

Download the list of datasets
Papers Phenotype Conditions Collection Tested mutants Data Details
Uluisik I~Koc A, 2011 growth (spot assay) boric acid [100 mM] hap a 4,732 Discrete
Uluisik I~Koc A, 2011 growth (spot assay) boric acid [20 mM] hap a 4,732 Discrete
Uluisik I~Koc A, 2011 growth (spot assay) boric acid [30 mM] hap a 4,732 Discrete
Uluisik I~Koc A, 2011 growth (spot assay) boric acid [40 mM] hap a 4,732 Discrete
Uluisik I~Koc A, 2011 growth (spot assay) boric acid [50 mM] hap a 4,732 Discrete
Uluisik I~Koc A, 2011 growth (spot assay) boric acid [60 mM] hap a 4,732 Discrete
Uluisik I~Koc A, 2011 growth (spot assay) boric acid [70 mM] hap a 4,732 Discrete
Uluisik I~Koc A, 2011 growth (spot assay) boric acid [125 mM] hap a 4,732 Discrete
Uluisik I~Koc A, 2011 growth (spot assay) boric acid [150 mM] hap a 4,732 Discrete

Curation history

Data

March 26, 2014 Data waiting for tested.
Nov. 17, 2014 Data to load.
Nov. 24, 2014 Data loaded.

Tested strains

March 26, 2014 Tested strains requested.
Nov. 11, 2014 Tested strains requested.
Nov. 17, 2014 Tested strains to load.
Nov. 24, 2014 Tested strains loaded.