Orij R~Smits GJ, 2012

Pubmed ID 23021432
Title Genome-wide analysis of intracellular pH reveals quantitative control of cell division rate by pH(c) in Saccharomyces cerevisiae.
Authors Rick Orij, Malene L Urbanus, Franco J Vizeacoumar, Guri Giaever, Charles Boone, Corey Nislow, Stanley Brul, Gertien J Smits
Abstract Because protonation affects the properties of almost all molecules in cells, cytosolic pH (pH(c)) is usually assumed to be constant. In the model organism yeast, however, pH(c) changes in response to the presence of nutrients and varies during growth. Since small changes in pH(c) can lead to major changes in metabolism, signal transduction, and phenotype, we decided to analyze pH(c) control.
Citation Genome Biol. 2012; 13:R80


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Paper Phenotype Condition Medium Collection Tested mutants Data Details
Orij R~Smits GJ, 2012 cytosolic pH standard SC(MSG) - Ura, low-fluor hap a 4,268 Quantitative

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