| Pubmed ID | 23552365 |
|---|---|
| Title | Genome-scale analyses of butanol tolerance in Saccharomyces cerevisiae reveal an essential role of protein degradation. |
| Authors | Daniel González-Ramos, Marcel van den Broek, Antonius Ja van Maris, Jack T Pronk, Jean-Marc G Daran |
| Abstract | n-Butanol and isobutanol produced from biomass-derived sugars are promising renewable transport fuels and solvents. Saccharomyces cerevisiae has been engineered for butanol production, but its high butanol sensitivity poses an upper limit to product titers that can be reached by further pathway engineering. A better understanding of the molecular basis of butanol stress and tolerance of S. cerevisiae is important for achieving improved tolerance. |
| Citation | Biotechnol Biofuels 2013; 6:48 |
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