Schlecht U~St Onge RP, 2014

Pubmed ID 24708151
Title A functional screen for copper homeostasis genes identifies a pharmacologically tractable cellular system.
Authors Ulrich Schlecht, Sundari Suresh, Weihong Xu, Ana Maria Aparicio, Angela Chu, Michael J Proctor, Ronald W Davis, Curt Scharfe, Robert P St Onge
Abstract Copper is essential for the survival of aerobic organisms. If copper is not properly regulated in the body however, it can be extremely cytotoxic and genetic mutations that compromise copper homeostasis result in severe clinical phenotypes. Understanding how cells maintain optimal copper levels is therefore highly relevant to human health.
Citation BMC Genomics 2014; 15:263

Datasets

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Paper Phenotype Condition Medium Collection Tested mutants Data Details
Schlecht U~St Onge RP, 2014 growth (relative abundance in pooled culture) copper(II) sulfate [500 mM] YPE [2%] hom 4,913 Quantitative
Schlecht U~St Onge RP, 2014 growth (relative abundance in pooled culture) copper(II) sulfate [500 mM] YPG [2%] hom 4,913 Quantitative
Schlecht U~St Onge RP, 2014 growth (relative abundance in pooled culture) copper(II) sulfate [500 mM] YPL [2%] hom 4,913 Quantitative
Schlecht U~St Onge RP, 2014 growth (relative abundance in pooled culture) copper(II) sulfate [500 mM] YPD hom 4,913 Quantitative

Curation history

Data

April 10, 2014 Ready to load.
March 15, 2016 Loaded.

Tested strains

April 10, 2014 Ready to load.
March 15, 2016 Loaded.