||A functional screen for copper homeostasis genes identifies a pharmacologically tractable cellular system.
||Ulrich Schlecht, Sundari Suresh, Weihong Xu, Ana Maria Aparicio, Angela Chu, Michael J Proctor, Ronald W Davis, Curt Scharfe, Robert P St Onge
||Copper is essential for the survival of aerobic organisms. If copper is not properly regulated in the body however, it can be extremely cytotoxic and genetic mutations that compromise copper homeostasis result in severe clinical phenotypes. Understanding how cells maintain optimal copper levels is therefore highly relevant to human health.
||BMC Genomics 2014; 15:263
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