| Pubmed ID | 16879425 |
|---|---|
| Title | The genome-wide screening of yeast deletion mutants to identify the genes required for tolerance to ethanol and other alcohols. |
| Authors | Katsuhide Fujita, Akinobu Matsuyama, Yoshinori Kobayashi, Hitoshi Iwahashi |
| Abstract | A set of homozygous diploid deletion mutants of the yeast Saccharomyces cerevisiae was screened for the genes required for tolerance to aliphatic alcohols. The screen identified 137, 122 and 48 deletion mutants sensitive to ethanol, 1-propanol and 1-pentanol, respectively. A number of the genes required for ethanol tolerance were those also required for tolerance to other alcohols. Numerous mutants with defective genes encoding for vacuolar H+ -ATPase (V-ATPase) were cosensitive to these alcohols. A global screening approach of yeast deletion library mutants was useful in elucidating the mechanisms of alcohol tolerance based on different lipophilicities. |
| Citation | FEMS Yeast Res. 2006; 6:744-50 |
YeastPhenome.org is running in beta version. The data are available for download, but, as of today, we cannot guarantee the absence of errors or code bugs introduced during processing. This warning will be removed after all cross-checks and validations have been completed. In the meantime, please, be careful when using the data.
| Nov. 2, 2016 | Request sent. |
| Nov. 2, 2016 | Not available. |
| Nov. 2, 2016 | Request sent. |
| Nov. 2, 2016 | Not available. |
| Nov. 2, 2016 | Ready to load. |
| April 18, 2017 | Loaded. |