Gaupel AC~Tenniswood M, 2014

Pubmed ID 24968945
Title High throughput screening identifies modulators of histone deacetylase inhibitors.
Authors Ann-Christin Gaupel, Thomas Begley, Martin Tenniswood
Abstract Previous studies from our laboratory and others have demonstrated that in addition to altering chromatin acetylation and conformation, histone deacetylase inhibitors (HDACi) disrupt the acetylation status of numerous transcription factors and other proteins. A whole genome yeast deletion library screen was used to identify components of the transcriptional apparatus that modulate the sensitivity to the hydroxamic acid-based HDACi, CG-1521.
Citation BMC Genomics 2014; 15:528

Datasets

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Paper Phenotype Condition Medium Collection Tested mutants Data Details
Gaupel AC~Tenniswood M, 2014 growth (spot assay) CG-1521 [55-75 uM] YPD hap a 4,784 Discrete

Curation history

Data

Nov. 10, 2014 Waiting for tested.
Nov. 11, 2014 Ready to load.
Nov. 19, 2014 Loaded.

Tested strains

Nov. 10, 2014 To request.
Nov. 11, 2014 Request sent.
Nov. 11, 2014 Ready to load.
Nov. 19, 2014 Loaded.