Jaime MD~Nislow C, 2012

Pubmed ID 22727066
Title Identification of yeast genes that confer resistance to chitosan oligosaccharide (COS) using chemogenomics.
Authors Maria D L A Jaime, Luis Vicente Lopez-Llorca, Ana Conesa, Anna Y Lee, Michael Proctor, Lawrence E Heisler, Marinella Gebbia, Guri Giaever, J Timothy Westwood, Corey Nislow
Abstract Chitosan oligosaccharide (COS), a deacetylated derivative of chitin, is an abundant, and renewable natural polymer. COS has higher antimicrobial properties than chitosan and is presumed to act by disrupting/permeabilizing the cell membranes of bacteria, yeast and fungi. COS is relatively non-toxic to mammals. By identifying the molecular and genetic targets of COS, we hope to gain a better understanding of the antifungal mode of action of COS.
Citation BMC Genomics 2012; 13:267


Download the list of datasets
Papers Phenotype Conditions Collection Tested mutants Data Details
Jaime MD~Nislow C, 2012 growth (relative abundance in pooled culture) time [20 generations], Chitosan oligosaccharide [91.1 ug/ml] het 970 Quantitative
Jaime MD~Nislow C, 2012 growth (relative abundance in pooled culture) Chitosan oligosaccharide [91.1 ug/ml], time [5 generations] hom 4,372 Quantitative

Curation history


Dec. 14, 2016 Data clarification needed.
Feb. 1, 2017 Data requested.
April 25, 2017 Data requested.
June 23, 2017 Data to load.
Sept. 24, 2017 Data loaded.

Tested strains

Feb. 1, 2017 Tested strains requested.
April 25, 2017 Tested strains requested.
June 23, 2017 Tested strains to load.
Sept. 24, 2017 Tested strains loaded.