Pir P~Oliver SG, 2012

Pubmed ID 22244311
Title The genetic control of growth rate: a systems biology study in yeast.
Authors Pınar Pir, Alex Gutteridge, Jian Wu, Bharat Rash, Douglas B Kell, Nianshu Zhang, Stephen G Oliver
Abstract Control of growth rate is mediated by tight regulation mechanisms in all free-living organisms since long-term survival depends on adaptation to diverse environmental conditions. The yeast, Saccharomyces cerevisiae, when growing under nutrient-limited conditions, controls its growth rate via both nutrient-specific and nutrient-independent gene sets. At slow growth rates, at least, it has been found that the expression of the genes that exert significant control over growth rate (high flux control or HFC genes) is not necessarily regulated by growth rate itself. It has not been determined whether the set of HFC genes is the same at all growth rates or whether it is the same in conditions of nutrient limitation or excess.
Citation BMC Syst Biol 2012; 6:4

Datasets

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Paper Phenotype Condition Medium Collection Tested mutants Data Details
Pir P~Oliver SG, 2012 growth (pooled culture) glucose limitation, chemostat, culture dilution rate [0.1/h] F1 (C-lim) het 5,508 Quantitative
Pir P~Oliver SG, 2012 growth (pooled culture) nitrogen limitation, chemostat, culture dilution rate [0.1/h] F1 (N-lim) het 5,537 Quantitative
Pir P~Oliver SG, 2012 growth (pooled culture) phosphorus limitation, chemostat, culture dilution rate [0.1/h] F1 (P-lim) het 5,507 Quantitative
Pir P~Oliver SG, 2012 growth (pooled culture) nitrogen limitation, chemostat, culture dilution rate [0.2/h] F1 (N-lim) het 5,494 Quantitative
Pir P~Oliver SG, 2012 growth (pooled culture) nitrogen limitation, chemostat, culture dilution rate [0.3/h] F1 (N-lim) het 5,580 Quantitative
Pir P~Oliver SG, 2012 growth (pooled culture) chemostat, culture dilution rate [0.3/h] FPM het 5,580 Quantitative
Pir P~Oliver SG, 2012 growth (pooled culture) turbidostat FPM het 5,580 Quantitative

Curation history

Data

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Tested strains

Aug. 29, 2017 Ready to load.
Oct. 10, 2017 Loaded.