Zhao Y~Deng Y, 2020

Pubmed ID 31836620
Title Saccharomyces cerevisiae.
Authors Yun-Ying Zhao, Chun-Lei Cao, Ying-Li Liu, Jing Wang, Jie Li, Shi-Yun Li, Yu Deng
Abstract 2 We showed that the intracellular ROS levels in 51 mutants were increased by high zinc stress, suggesting their possible involvement in regulating ROS homeostasis in response to high zinc. The results also revealed that excess zinc could generate oxidative damage and then activate the expression of several antioxidant defenses genes. Taken together, the data obtained indicated that excess zinc toxicity might be mainly due to the high intracellular zinc levels and ROS levels induced by zinc stress in yeast cells. Our current findings would provide a basis to understand the molecular mechanisms of zinc toxicity in yeast cells.
Citation G3 (Bethesda) 2020; 10:479-488

Datasets

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Paper Phenotype Condition Medium Collection Tested mutants Data Details
Zhao Y~Deng Y, 2020 growth (culture turbidity) zinc dichloride [3 mM] YPD hom ~4,757 Discrete

Curation history

Data

May 20, 2020 To request.
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Tested strains

May 20, 2020 To request.
May 20, 2020 Request sent.