||Genome-wide survey of yeast mutations leading to activation of the yeast cell integrity MAPK pathway: novel insights into diverse MAPK outcomes.
||Patricia Arias, Sonia Díez-Muñiz, Raúl García, César Nombela, José M Rodríguez-Peña, Javier Arroyo
||The yeast cell wall integrity mitogen-activated protein kinase (CWI-MAPK) pathway is the main regulator of adaptation responses to cell wall stress in yeast. Here, we adopt a genomic approach to shed light on two aspects that are only partially understood, namely, the characterization of the gene functional catalog associated with CWI pathway activation and the extent to which MAPK activation correlates with transcriptional outcomes.
||BMC Genomics 2011; 12:390
||Deletion collection was screened for strains with constitutive transcriptional activation of MLP1 (cell wall integrity pathway).
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