Zeidler U~d'Enfert C, 2013

Pubmed ID 23378416
Title Synergy of the antibiotic colistin with echinocandin antifungals in Candida species.
Authors Ute Zeidler, Marie-Elisabeth Bougnoux, Alexandru Lupan, Olivier Helynck, Antonia Doyen, Zacarias Garcia, Natacha Sertour, Cécile Clavaud, Hélène Munier-Lehmann, Cosmin Saveanu, Christophe d'Enfert
Abstract Candida albicans is the most prevalent fungal pathogen of humans, causing a wide range of infections from harmless superficial to severe systemic infections. Improvement of the antifungal arsenal is needed since existing antifungals can be associated with limited efficacy, toxicity and antifungal resistance. Here we aimed to identify compounds that act synergistically with echinocandin antifungals and that could contribute to a faster reduction of the fungal burden.
Citation J. Antimicrob. Chemother. 2013; 68:1285-96

Datasets

Download the list of datasets
Paper Phenotype Condition Medium Collection Tested mutants Data Details
Zeidler U~d'Enfert C, 2013 growth (pooled culture, microarray) Aminocandin [0.00125 mg/L] YPD hap a ~4,885 Unknown
Zeidler U~d'Enfert C, 2013 growth (pooled culture, microarray) Aminocandin [0.002 mg/L] YPD het ~5,936 Unknown
Zeidler U~d'Enfert C, 2013 growth (pooled culture, microarray) colistin [20 mg/L] YPD hap a ~4,885 Unknown
Zeidler U~d'Enfert C, 2013 growth (pooled culture, microarray) Aminocandin [0.00125 mg/L], colistin [5 mg/L] YPD hap a ~4,885 Unknown
Zeidler U~d'Enfert C, 2013 growth (pooled culture, microarray) colistin [30 mg/L] YPD het ~5,936 Unknown
Zeidler U~d'Enfert C, 2013 growth (pooled culture, microarray) Aminocandin [0.002 mg/L], colistin [10 mg/L] YPD het ~5,936 Unknown

Curation history

Tested strains

July 2, 2020 To request.
July 27, 2020 Request sent.

Data

July 2, 2020 To request.
July 27, 2020 Request sent.