YeastPhenome.org is a collaborative project that aims at constructing a comprehensive compendium of systematic phenotypic data for budding yeast Saccharomyces cerevisiae.
Our goal is to collect, process and share in a standardized format the results of all genome-scale experiments that have examined the yeast deletion collection for any given phenotype under any given experimental condition.
In order to be included in the compendium, a study must meet all of the following criteria:
Our primary source of data are the supplementary materials of the relevant publications. On top of that, many authors have contributed more complete and previously unpublished versions of their datasets (e.g., raw quantitative values from which the published hit list was derived). These datasets are explicitly flagged to emphasize their special status.
The individual datasets are available for download as soon as they are curated (e.g., see the green "Download all data" button for Bleackley MR~MacGillivray RT, 2011). The full compendium of all datasets will be accessible later on, as soon as we finalize the standardized nomenclature of phenotypes and experimental conditions.
Yeastphenome.org was created and is being maintained by:
— The Yeast Phenome Database, www.yeastphenome.org, accessed on XXXX-XX-XX.
Updated automatically on Sept. 27, 2020.
|Strain background||Number of datasets|
|Haploid Mat-a||892 (6%)|
|Haploid Mat-alpha||6,221 (39%)|
|Homozygous diploid||4,442 (28%)|
|Heterozygous diploid||4,388 (27%)|
|Data type||Number of datasets|
|Quantitative only for hits||253 (2%)|
|Condition type||Number of papers||Number of datasets|
|temperature||30||104 (48 q + 3 qofh + 53 d)|
|methyl methanesulfonate||18||28 (21 q + 4 qofh + 3 d)|
|sodium chloride||17||58 (48 q + 1 qofh + 9 d)|
|hydroxyurea||14||32 (25 q + 2 qofh + 5 d)|
|ethanol||13||17 (4 q + 1 qofh + 12 d)|
|sirolimus||12||34 (29 q + 0 qofh + 5 d)|
|tunicamycin||12||20 (15 q + 1 qofh + 4 d)|
|hydrogen peroxide||12||21 (17 q + 1 qofh + 3 d)|
|cycloheximide||11||18 (13 q + 1 qofh + 4 d)|
|camptothecin||11||21 (18 q + 2 qofh + 1 d)|
|Phenotype class||Number of datasets (hap/hom)||Number of papers (hap/hom)||Number of datasets (het)||Number of papers (het)|
|Growth||4,803 (42%)||267||4,369 (100%)||42|
|Expression||6,125 (53%)||6||0 (0%)||0|
|Other||640 (6%)||117||19 (0%)||6|
What you see on this website is the ChEBI or the PubChem name of the drugs. Whenever possible, we associate chemical compounds with a ChEBI ID (preferentially) or a PubChem ID (if ChEBI ID was not available) and display, by default, their ChEBI or PubChem names, respectively. This sometimes results in an unusual name (e.g., the ChEBI name of rapamycin is sirolimus), but it greatly facilitates the consistency of the data. The original drug names (those used in the paper) are still available through search and will soon be displayed on the condition page.