|Title||Genomic phenotyping of the essential and non-essential yeast genome detects novel pathways for alkylation resistance.|
|Authors||J Peter Svensson, Laia Quirós Pesudo, Rebecca C Fry, Yeyejide A Adeleye, Paul Carmichael, Leona D Samson|
|Abstract||A myriad of new chemicals has been introduced into our environment and exposure to these agents can damage cells and induce cytotoxicity through different mechanisms, including damaging DNA directly. Analysis of global transcriptional and phenotypic responses in the yeast S. cerevisiae provides means to identify pathways of damage recovery upon toxic exposure.|
|Citation||BMC Syst Biol 2011; 5:157|
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|March 8, 2013||Data loaded.|
|March 8, 2013||Tested strains loaded.|