Jaeger PA~Ideker T, 2018

Pubmed ID 29351850
Title Systematic Gene-to-Phenotype Arrays: A High-Throughput Technique for Molecular Phenotyping.
Authors Philipp A Jaeger, Lilia Ornelas, Cameron McElfresh, Lily R Wong, Randolph Y Hampton, Trey Ideker
Abstract 34 tRNA modification, which acts independently of proteasomal degradation to limit misfolded protein production. Integration of SGPA with other fluorescent readouts will enable genetic dissection of a wide range of biological pathways and conditions.
Citation Mol. Cell 2018; 69:321-333.e3

Datasets

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Paper Phenotype Condition Medium Collection Tested mutants Data Details
Jaeger PA~Ideker T, 2018 growth (colony size) glucose [2%] hom N/A Quantitative only for hits
Jaeger PA~Ideker T, 2018 growth (colony size) galactose [2%] hom N/A Quantitative only for hits
Jaeger PA~Ideker T, 2018 degradation of misfolded proteins (ΔssCPY*-GFP) standard hom N/A Quantitative only for hits
Jaeger PA~Ideker T, 2018 expression level of a gene (pGAL1-GFP) glucose [2%] hom N/A Quantitative only for hits
Jaeger PA~Ideker T, 2018 expression level of a gene (pGAL1-GFP) galactose [2%] hom N/A Quantitative only for hits

Curation history

Data

Feb. 12, 2018 To request.
March 9, 2018 Request sent.
March 12, 2018 Ready to load.

Tested strains

Feb. 12, 2018 To request.
March 9, 2018 Request sent.
March 12, 2018 Ready to load.