Merz S~Westermann B, 2009

Pubmed ID 19751518
Title Genome-wide deletion mutant analysis reveals genes required for respiratory growth, mitochondrial genome maintenance and mitochondrial protein synthesis in Saccharomyces cerevisiae.
Authors Sandra Merz, Benedikt Westermann
Abstract The mitochondrial respiratory chain produces metabolic energy by oxidative phosphorylation. Biogenesis of the respiratory chain requires the coordinated expression of two genomes: the nuclear genome encoding the vast majority of mitochondrial proteins, and the mitochondrial genome encoding a handful of mitochondrial proteins. The understanding of the molecular processes contributing to respiratory chain assembly and maintenance requires the systematic identification and functional analysis of the genes involved.
Citation Genome Biol. 2009; 10:R95


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Paper Phenotype Condition Medium Collection Tested mutants Data Details
Merz S~Westermann B, 2009 growth (spot assay) standard YPG [3%] hap alpha 4,894 Discrete

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